Analysis of North American Rheumatoid Arthritis Consortium data using a penalized logistic regression approach
نویسندگان
چکیده
We applied a penalized regression approach to single-nucleotide polymorphisms in regions on chromosomes 1, 6, and 9 of the North American Rheumatoid Arthritis Consortium data. Results were compared with a standard single-locus association test. Overall, the penalized regression approach did not appear to offer any advantage with respect to either detection or localization of disease-associated polymorphisms, compared with the single-locus approach.
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2009